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Cell Freeze® Cryogenic Containers

​Charter Medical’s Cell Freeze® cryogenic storage containers are designed for storage, preservation, and transfer of hematopoietic progenitor cells (HPCs).

Cell Freeze® Design

  • Container material suitable for use at ultra-low temperatures (-196 C)
  • Membrane port for addition or removal of contents
  • Industry-standard label pocket design offers ease of use and label traceability

Features and Benefits

  • Polyolefin Film – EVA-blend specifically selected for its low temperature properties and clarity when filled with liquid.
  • Membrane Port – The attached cap snaps into place to protect the contents and minimizes membrane exposure when not in use.
  • Label Pocket – Supports use of computer-generated labels. Critical information can be viewed quickly by simply opening the freezing cassette.
  • Interface/Connectors – Compatible with commercially available tube welding and freezing cassette systems.

Physical Integrity

Container was evaluated for the ability to withstand temperature variations experienced during routine storage of HPC products. Product qualification passed physical integrity tests, including an initial pressure test, leak test, microbial challenge, and dye immersion tests.

Cell Quality

Cell quality was assessed using MNC and CD34+ cells suspended in 10% dimethyl sulfoxide (DMSO). Results met the acceptance requirement for MNC and CD34+ cell recovery of ≥ 70% relative to cell counts of the sample prior to cryopreservation. The average MNC and CD34+ cell recoveries were 81% and 84% respectively.

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